Complete a written report (2000 words not including figures, tables and references – Vancouver style; avoid textbooks, lecture slides) of the profile of the drug you are allocated.
Start with introduction.
The following must be discussed in your written report (see marking rubric):
a) Pharmacology (mechanism of action, toxicities/adverse effects)
b) Clinical uses
c) Dosages/formulations available
d) Chemical structures related to pharmacokinetic parameters
e) Interesting pharmacokinetic parameters (ADME, CL, Vd, k, t½…) and clinical implications
f) Requirement for Therapeutic Drug Monitoring (TDM)
g) Considerations when the drug is used in special populations (e.g. change in pharmacokinetic parameters and dose adjustments in a renally or hepatically impaired patient, an overweight patient or an infant)
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