DNA Kit Assignment | Homework For You
INSTRUCTIONS: The titles and weblinks of two articles are cited below. Read these articles and answer the questions. In some of your answers, you will need to bring in information from a source other than the two articles. In these cases, please simply provide a citation (in any format that would allow someone to look up the citation). You need not cite either of the two articles below in your answers – I will assume you are referring to the articles unless you indicate otherwise. We will be having a discussion in lecture based on the content and ideas of these articles. ARTICLES: A) Guinto, Joseph. “Why is this $99 home DNA kit causing such an uproar?” Genome Magazine (30 Nov. 2016) B) Salamon, Maureen. “The Ultimate Selfie”. Genome Magazine (30 Nov. 2016) QUESTIONS:
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1) What is the definition of “personalized medicine” and how does it relate to personal genetic testing? [3 points]
2) What is the meaning of the brand name “23andMe”? [2 points] 3) Based on what reasoning has the FDA imposed strict regulations on services provided by 23andMe? [3 points]
4) According to the first article, what is considered an “ideal” outcome from someone who has undergone personal genetic testing? [2 points]
5) In one of your BIO-110 laboratory exercises, you tested for SNPs in the CDK3 gene using PCR and the HpaII enzyme. What are “SNPs” and how are they informative for genetic testing? [3 points]
6) Why can diagnostic genetic testing only predict if you are at risk for developing a disease, instead of definitively determining whether you will be afflicted with the disease? [2 points]
7) a) Briefly describe what information is provided by the following types of personal genetic tests: [6 points total] i) Whole Genome Sequencing (WGS) ii) Whole Exome Sequencing iii) 23andMe Direct-to-Consumer tests
8) What is the premise of the Genetic Information Nondiscrimination Act (GINA) of Congress? [3 points]
9) What are “pharmacogenomic” analyses and how can data from personal genetic tests facilitate these? [3 points]
10) Besides facilitating pharmacogenomic analyses, what are two other beneficial aspects of genetic testing? [2 points]
11) What are two consequences of genetic testing that our society should be wary of? [2 points]
12) UV-induced damage of the tumor suppressor gene p53 can lead to skin cancer. Suppose an individual recently acquired a spontaneous mutation in the p53 gene of a skin cell. If this person then underwent a 23andMe analysis, would the test be able to detect this newly introduced predisposition to skin cancer? Why or why not? [4 points]
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13) From the list below, indicate all categories of information, if any, you would be interested in determining about yourself from genetic testing (with a system like 23andMe). [1 point] nothing possible reactions information about information about information prefer to drugs ancestory certain diseases of all disease not to only (ex.non-lethal) predispositions say. Get Biology homework help today
